Brugada syndrome: clinical and genetic findings
نویسندگان
چکیده
منابع مشابه
The Brugada syndrome: clinical, electrophysiologic and genetic aspects.
This review deals with the clinical, basic and genetic aspects of a recently highlighted form of idiopathic ventricular fibrillation known as the Brugada syndrome. Our primary objective in this review is to identify the full scope of the syndrome and attempt to correlate the electrocardiographic manifestations of the Brugada syndrome with cellular and ionic heterogeneity known to exist within t...
متن کاملGenetic Basis of Brugada Syndrome
Brugada syndrome is a rare cardiac disorder described as a clinical entity in 1992. It is characterized by typical electrocardiographic alteration in a structurally normal heart, and associated with a high risk of sudden cardiac death. Brugada syndrome affects mainly young adult males and patients can present a wide range of symptoms or even remain asymptomatic. The first genetic basis responsi...
متن کاملGenetic testing in Brugada syndrome.
Brugada syndrome (BrS) is a hereditary arrhythmic disorder associated with a right ventricular conduction delay and ST-segment elevation in the right precordial leads and syncope and sudden death due to ventricular fibrillation (1). The type 1 Brugada electrocardiographic ECG pattern (coved ST-segment elevations in leads V1 to V3) is a ynamic finding that may be present at baseline or may ecome...
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In order to identify the clinical and electrophysiological characteristics of childhood Guillain-Barre Syndrome (GBS) in East Azarbaijan province, clinical and electrophysiological data on 40 consecutive children with GBS, admitted to Tabriz Children's Medical Center from March 21st 1999 to March 20th 2002, were analyzed. All patients received intravenous immunoglobulin, 400 mg /kg/ day fo...
متن کاملThe genetic component of Brugada syndrome
Brugada syndrome (BrS) is a clinical entity first described in 1992. BrS is characterized by ST-segment elevations in the right precordial leads and susceptibility to ventricular arrhythmias and sudden cardiac death. It affects young subjects, predominantly males, with structurally normal hearts. The prevalence varies with ethnicity ranging from 1:2,000 to 1:100,000 in different parts of the wo...
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ژورنال
عنوان ژورنال: Genetics in Medicine
سال: 2015
ISSN: 1098-3600,1530-0366
DOI: 10.1038/gim.2015.35